研究業績

  • Hara T, Katoh H, Ogawa D, Kagaya Y, Sato Y, Kitano H, Nagato Y, Ishikawa R, Ono A, Kinoshita T, Takeda S, *Hattori T. Rice SNF2 family helicase ENL1 is essential for syncytial endosperm development. Plant J. 81:1-12 (2015)
  • *Buzas DM , Nakamura M, and *Kinoshita T. Epigenetic role for the conserved Fe-S cluster biogenesis protein AtDRE2 in Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA 111:13655-70 (2014)
  • Kurusu T, Koyano T, Hanamata S, Kubo T, Noguchi Y, Yagi C, Nagata N, Yamamoto T, Ohnishi T, Okazaki Y, Kitahata N, Ando D, Ishikawa M, Wada S, Miyao A, Hirochika H, Shimada H, Makino A, Saito K, Ishida H, Kinoshita T, Kurata N, Kuchitsu K. OsATG7 is required for autophagy-dependent lipid metabolism in rice postmeiotic anther development. Autophagy Mar 24;10 (5) (Epub ahead of print) (2014)
  • Sekine D., Ohnishi T., Furuumi H, Ono A., Yamada T., Kurata N., *Kinoshita T. Dissection of two major components of the post-zygotic hybridization barrier in rice endosperm. Plant J. 76: 792-799. (2013)
  • Vu TM., Nakamura M., Calarco JP., Susaki D., Lim PQ., Kinoshita T., Higashiyama T., Martienssen RA., *Berger F. RNA-directed DNA methylation controls parental imprinting in Arabidopsis. Development 140: 2953-2960. (2013)
  • *Ohnishi T., Yoshino M., Toriyama K., *Kinoshita T. Rapid establishment of introgression lines through cytoplasmic male sterility and its restorer gene in Oryza Sativa cv. Nipponbare. Molecular Breeding 32: 831-839. (2013)
  • Nakamura M, Kato A, Fujia M., Kinoshita Y, Kurata N, *Kinoshita T. Mutation in NAR1, a and confers paraquat resistance during vegetative growth. New Phytologist 199: 925-935. (2013)
  • Ikeda Y., Kinoshita Y., Susaki D., Ikeda Y., Iwano M., Takayama S., Higashiyama T., Kakutani T., *Kinoshita T. HMG domain containing SSRP1 is required for DNA demethylation and genomic imprinting in Arabidopsis. Developmental Cell 21(3): 589-96. (2011)
  • Ohnishi T., Yoshino M, Yamakawa H, *Kinoshita T. The biotron breeding system: a rapid and reliable procedure for genetic studies and breeding in rice. Plant Cell Physiol. 52: 1249-57. (2011) Editor in Chief’s Choice平成24年度日本植物生理学会Plant Cell Physiology論文賞受賞
  • Ishikawa R., Ohnishi T., Kinoshita Y., Eiguchi M., Kurata N., *Kinoshita T. Rice interspecies hybrids show precocious or delayed developmental transitions in the endosperm without change to the rate of syncytial nuclear division. Plant J. 65:798-806. (2011)
  • Tiwari S., Schulz R., Ikeda Y., Dytham L., Bravo J., Mathers L., Spielman M., Guzmán P., Oakey RJ., Kinoshita T., and Scott RJ. MATERNALLY EXPRESSED PAB C-TERMINAL, a Novel Imprinted Gene in Arabidopsis, Encodes the Conserved C-Terminal Domain of Polyadenylate Binding Proteins Plant Cell 20: 2387-2398. (2008)
  • Fujimoto R., Kinoshita Y., Kawabe A., Kinoshita T., Takashima K., Nordborg M., Nasrallah ME., Shimizu KK., Kudoh H., Kakutani T. Evolution and control of imprinted FWA genes in the genus Arabidopsis. PLoS Genetics 4, (4) e1000048. (2008)
  • Kinoshita Y., Saze H., Kinoshita T., Miura A., Soppe W., Koornneef M., Kakutani, T., Control of FWA gene silencing in Arabidopsis thaliana by SINE-related direct repeats. Plant J. 49: 38-45. (2007)
  • Jullien PE., Kinoshita T., Ohad N., Berger F. Maintenance of DNA Methylation during the Arabidopsis Life Cycle Is Essential for Parental Imprinting. Plant Cell 18: 1360-1372. (2006)
  • Kakutani T., Kato M., Kinoshita T., Miura A. Control of Development and Transposon Movement by DNA Methylation in Arabidopsis thaliana. Cold Spring Harbor Symposia on Quantitative Biology 69, 139-143. (2005)
  • *Kinoshita T., Miura A., Choi Y., Kinoshita Y., Cao X., Jacobsen SE, Fischer RL, *Kakutani T. One-way control of FWA imprinting in Arabidopsis endosperm by DNA methylation. Science 303:521-523. (2004)
  • Kinoshita T., Harada JJ., Goldberg RB, Fischer RL. Polycomb repression of flowering during early plant development. Proc. Natl. Acad. Sci. USA 98: 14156-14161. (2001)
  • Yadegari R., Kinoshita T., Lotan O., Cohen G., Katz A., Choi Y., Katz A., Nakashima K., Harada JJ., Goldberg RB., Fischer RL., Ohad N. Mutations in the FIE and MEA genes that encode interacting polycomb proteins cause parent-of-origin effects on seed development by distinct mechanisms. Plant Cell 12: 2367-2382. (2000)
  • Kinoshita T., Yadegari R., Harada JJ., Goldberg RB, Fischer RL. Imprinting of the MEDEA polycomb gene in the Arabidopsis endosperm. Plant Cell 11; 1945-1952. (1999)
  • Kinoshita T., Yamada K., Hiraiwa N, Kondo M., Nishimura M., Hara-Nishimura I. Vacuolar processing enzyme is up-regulated in the lytic vacuoles of vegetative tissues during senescence and under various stressed conditions. Plant J. 19: 43-53. (1999)
  • Hara-Nishimura I., Kinoshita T., Hiraiwa N., Nishimura M. Vacuolar processing enzymes in protein-storage vacuoles and lytic vacuoles. J. Plant Physiol 152: 668-674. (1998)
  • Kinoshita T., Nishimura M., Hara-Nishimura I. Homologues of a vacuolar processing enzyme that are expressed in different organs in Arabidopsis thaliana. Plant Mol. Biol. 29; 81-89. (1995)
  • Kinoshita T., Nishimura M., Hara-Nishimura I. The sequence and expression of the third gannma-VPE gene, one member of a family of three genes for vacuolar processing enzymes in Arabidopsisi thaliana Plant Cell Physiol. 36; 1555-1562. (1995)
  • Kageyama Y., Kinoshita T., Umesono Y., Hatakeyama M., Oishi K. Cloning of cDNA for vitellogenin of Athalia rosae (Hymenoptera) and characterization of the vitellogenin gene expression. Insect Mol. Biol. 24; 599-605. (1995)
  • Hatakeyama M., Kageyama Y., Kinoshita T., Oishi K. Completion of development in Athalia rosae (Hmenoptera) eggs matured with heterospecific Athalia infumata yolk protein. J. Insect Physiol. 41; 351-355. (1995)
  • Kinoshita T., Hara-Nishimura I, Shiraishi H., Okada K, Shimura Y, Nishimura M. Nucleotide sequence of a transmenbrane protein (TMP-C) cDNA in Arabidopsis thaliana. Plant Physiol. 105; 1441-1442. (1994)
  • Kinoshita T., Fukuzawa H, Shimada T., Saito T., Matsuda Y. Primary structure and expression of a gamete lytic enzyme in Chlamydomonas reinhardtii: Simirarity of functional domains to matrix metalloproteases. Proc. Natl. Acad. Sci. USA 89; 4693-4697. (1992)
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英文総説・その他

  • Tonosaki K, Kinoshita T. Possible roles for polycomb repressive complex 2 in cereal endosperm. Front. Plant Sci. 6:144 eCollection (2015)
  • *Kinoshita T, Seki M. Epigenetic Memory for Stress Response and Adaptation in plants. Plant Cell Physiol. Oct 8. pii: pcu125. [Epub ahead of print] (2014)
  • Ohnishi T, Sekine D, Kinoshita T. Genomic imprinting in plants: what makes the functions of paternal and maternal genes different in endosperm formation? Adv Genet. 86:1-25. (2014)
  • *Kinoshita T. Jacobsen SE. Opening the Door to Epigenetics in PCP. Plant Cell Physiol. 53: 763-765. (2012)
  • Ishikawa R., *Kinoshita T. Epigenetic reprogramming; challenge to species hybridization. Molecular Plant 2: 589-599. (2009)
  • Ikeda Y., *Kinoshita T. DNA demethylation: a lesson from the garden. Chromosoma 118: 37-41. (2009)
  • *Kinoshita T., Ikeda Y., Ishikawa R. Genomic imprinting: A balance between antagonistic roles of parental chromosomes. Seminars in Cell and Developmental Biology 19: 574-579. (2008)
  • *Kinoshita T. Reproductive Barrier and Genomic Imprinting in the Endosperm of Flowering Plants. Genes& Genetic System 82: 177-186. (2007)
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著書総説等

  • 木下哲、小野明美、RdDM を介した植物におけるエピジェネティック変異の誘導と後代への伝達、“Induction of epigenetic modifications by RNA-directed DNA methylation (RdDM) and their inheritance to the next generation in plants”、植物の生長調節、48(2): 142-147 (2013)
  • 前川 雅彦、金澤 章、堤 伸浩、木下 哲、土生 芳樹、柴 博史、江面 浩
    「エピミュータジェネシスと次世代育種への展開」、育種学研究 15:42-50 (2013)
  • 木下 哲、「植物生殖過程におけるエピジェネティックな情報のリプログラミング」Epigenetic reprograming of maternal and paternal genome during plant sexual reproduction. Leading Author’s、ライフサイエンス領域融合レビュー、2:e001 (2013) (査読有り) http://leading.lifesciencedb.jp/2-e001/336/#-more-336
  • 池田 陽子、木下 哲、「シロイヌナズナにおけるゲノムインプリンティングとDNAの脱メチル化の制御にはHMGドメインを含むタンパク質SSRP1をコードする遺伝子が必要である」。First Author’s、ライフサイエンス新着論文レビュー、(2011)http://first.lifesciencedb.jp/archives/3658#more-3658(2011)
  • 池田 陽子、木下 哲、 「HMG遺伝子SSRP1はシロイヌナズナにおけるDNA脱メチル化およびゲノムインプリンティングに必要である」、細胞工学 学研メディカル秀順社 第30巻、p1296-1297 (2011)
  • 木下 哲、「細胞履歴に基づく植物の形態形成」、「植物のゲノムインプリンティングと胚乳発生制御機構」、p35-47 高等研報告書、研究代表者; 鎌田 博、ISBN:978–4–906671 -81-6 (2011)
  • 木下 哲、「ゲノムが拓く生態学」、「ゲノムに刷り込まれた生殖隔離」、種生物学会編、 文一総合出版、p141-155. (2011)
  • 中村 みゆき、木下 哲、「ゲノムが拓く生態学」、「エピジェネティクス」、種生物学会編、文一総合出版、 p109-122. (2011)
  • 大西 孝幸、木下 哲、「Early development of rice endosperm」、 Plant Morphology 22: 15-22. (2010)
  • 池田 陽子、木下 哲、「ゲノムインプリンティング」、細胞工学・別冊・植物細胞工学シリーズ24、植物のエピジェネティクス、秀順社、 p129-135 (2008)
  • 木下 哲、池田 陽子、石川 亮、「ポリコーム複合体による植物の発生制御」、植物の生長調節 43 (1) 29-34 (2008)
  • 星野 敦、木下 哲、「反復配列・DNAメチル化により制御される植物の生命現象」、 化学と生物 Vol. 45, p119-125. (2007)
  • 木下 哲、角谷徹仁、「植物におけるゲノムインプリンティング機構」、Molecular Medicine (中山書店)vol. 42, p. 189-194. (2005)
  • 木下 哲、角谷徹仁、「エピジェネティクス(佐々木裕之編)」「植物のゲノムインプリンティング」、シュプリンガーフェアラーク社、p. 173-179. (2004)
  • 角谷徹仁、木下 哲、「クロマチンと遺伝子機能制御(掘越正美編)」「植物のエピジェネティクス」、シュプリンガーフェアラーク社、p. 241-251. (2003)